Arcutis Biotherapeutics And Kowa Pharmaceuticals America Terminate Promotion Agreement Covering Zoryve (roflumilast) By Kowa To Primary Care Physicians And Pediatricians In US

Following the termination, Arcutis plans to assume responsibility for sales and promotion of ZORYVE in the pediatric and primary care settings. The Company is finalizing its plans for promotion to these clinicians and will provide further updates during the Q4 earnings call on February 25, 2026. This initiative is distinct from and in addition to the targeted expansion of the Company's dermatology salesforce, which will remain focused on serving dermatology clinicians and growing prescriptions of ZORYVE in dermatology practices.

"Our promotion agreement with Kowa has laid important groundwork for the promotion of ZORYVE in the primary care and pediatric markets," said Frank Watanabe, president and CEO of Arcutis. "As a once-daily topical that can be used anywhere on the body and for any duration, ZORYVE has the potential to simplify disease management across three major inflammatory skin diseases. In 2026, we are well-positioned to drive adoption and growth of ZORYVE in the primary care market through incremental investments that we will scale over time, while maximizing the growth of ZORYVE in dermatology."

Under the terms of the Termination Agreement, Kowa will cease all sales and promotions of ZORYVE and Arcutis will not be required to make any further payments. The Company expects to remain cash flow break even and does not expect this change to negatively affect 2026 net product sales guidance.